Chuck Lorre Productions

The lives of four socially awkward scientists take a wild turn when a beautiful and free-spirited girl moves in next door.

A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.

Meet a child genius named Sheldon Cooper (already seen as an adult in The Big Bang Theory (2007)) and his family. Some unique challenges face Sheldon, who is socially impaired.

An aging actor, who long ago enjoyed a brush with fame, makes his living as an acting coach.

A newly sober single mom tries to pull her life together in Napa Valley while dealing with her wayward mother.

A couple meets at an Overeaters' Anonymous meeting.

Georgie and Mandy navigate the challenges of adulthood, parenting and marriage while raising their young family in Texas.

Follows a veteran bookie struggling to survive the impending legalization of sports gambling, increasingly unstable clients, family and co-workers.

An American guy falls in love with his Nigerian nurse.

A grandmother's life is upended when her husband leaves her after 33 years of marriage. She navigates this new chapter with the help of her family, grace, dignity, and jello salad.

The friendship between Riley, a Marine combat veteran struggling to readjust to civilian life in Ohio, and Awalmir, the Afghan interpreter who served with his unit and has just arrived to start a new life in America.

Newly divorced dad Drew faces finding a kidney donor and is at the end of his rope and his hope when he runs into Gina, a rough-around-the edges woman from his past who volunteers her own.

Comic book store owner Stuart Bloom from The Big Bang Theory (2007) returns in a new series where he attempts - and apparently fails - to save the universe, staying true to his unlucky nature.